We present multi-color imaging by stimulated Raman scattering (SRS) enabled by an ultrafast fiber-based light source with integrated amplitude modulation and frame-to-frame wavelength tuning. With a relative intensity noise level of -153.7 dBc/Hz at 20.25 MHz the light source is well suited for SRS imaging and outperforms other fiber-based light source concepts for SRS imaging. The light source is tunable in under 5 ms per arbitrary wavelength step between 700 cm−1 and 3200 cm−1, which allows for addressing Raman resonances from the fingerprint to the CH-stretch region. Moreover, the compact and environmentally stable system is predestined for fast multi-color assessments of medical or rapidly evolving samples with high chemical specificity, paving the way for diagnostics and sensing outside of specialized laser laboratories.
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- TitelMulti-color stimulated Raman scattering with a frame-to-frame wavelength-tunable fiber-based light source
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- AnmerkungReal-time imaging of the dDMSO (2125 cm^(-1)) and lipid (2850 cm^(-1)) resonances with stimulated Raman scattering with frame-to-frame wavenumber-switching (256x256 pixels, no averaging) available at https://doi.org/10.6084/m9.figshare.14939160.v1.
- SpracheEnglisch
- Bibl. ReferenzBiomedical Optics Express 12 (2021) 10, 6228-6236
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