A general analytical theory of temporal relaxation processes in isolated quantum systems with many degrees of freedom is elaborated, which unifies and substantially amends several previous approximations. Specifically, the Fourier transform of the initial energy distribution is found to play a key role, which is furthermore equivalent to the so-called survival probability in case of a pure initial state. The main prerequisite is the absence of any notable transport currents, caused for instance by some initially unbalanced local densities of particles, energy, and so on. In particular, such a transportless relaxation scenario naturally arises when both the system Hamiltonian and the initial non-equilibrium state do not exhibit any spatial inhomogeneities on macroscopic scales. A further requirement is that the relaxation must not be notably influenced by any approximate (but not exact) constant of motion or metastable state. The theoretical predictions are compared with various experimental and numerical results from the literature.